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Pancytopenia is one kind of disease where three main components of blood reduce.It is the number of reduction of RBCs,WBCs and platelets in the peripheral blood.
It is the combination of anaemia,leukopenia and thrombocytopenia.
1.Anaemia-In this case,RBCs reduces. 2.Leukopenia-In this case,WBCs reduces.
3 . Thrombocytopenia-In this case,platelet reduces. But the ration of reduction varies in both male and female.
Causes:
1.Marrow space occupying lesions.
2.Decreased production of blood cells.
3.Defective stem cells.
4.Deficiency of factors stimulating haematopoiesis.
5.Lymphoma.
6.Vitamin B-12 and Folic acid deficiency etc.
How can we evaluate pancytopenia in lab:
1.CBC with peripheral blood smear.
2.Bone-marrow aspiration.
3.Specific investigation .
Before staring any treatment,some parameters must be emphasized:
1.Age 2.Sex 3.Duration of symptoms 4.Joint pain 5.Bone pains,fever,night sweats,weight loss etc
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